Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up
In: Journal of psychopharmacology (Oxford), Jg. 22 (2008), Heft 7, S. 805-808
Online
academicJournal
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Zugriff:
Borderline patients often display pathological aggression. We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287-291), and found significant changes on most scales of the State-Trait Anger Expression Inventory (STAXI) after eight weeks. To assess the longer-term efficacy of lamotrigine in therapy for aggression in women with BPD, this 18-month follow-up observation was carried out, in which patients (treated with lamotrigine: n = 18; former placebo group: n = 9) were tested every six months. According to the intent-to-treat principle, significant changes on all scales of the STAXI were observed in the lamotrigine-treated subjects. All subjects tolerated lamotrigine relatively well. Lamotrigine appears to be an effective and relatively safe agent in the longer-term treatment of aggression in women with BPD.
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Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up
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Autor/in / Beteiligte Person: | LEIBERICH, P ; NICKEL, M. K ; TRITT, K ; PEDROSA GIL, F |
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Zeitschrift: | Journal of psychopharmacology (Oxford), Jg. 22 (2008), Heft 7, S. 805-808 |
Veröffentlichung: | London: Sage, 2008 |
Medientyp: | academicJournal |
Umfang: | print, 1/2 p |
ISSN: | 0269-8811 (print) |
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