Premorbid psychosocial factors are associated with poor health-related quality of life in subjects with new onset of chronic widespread pain : Results from the EPIFUND study
In: Pain (Amsterdam), Jg. 141 (2009), Heft 1-2, S. 119-126
academicJournal
- print, 46 ref
Zugriff:
Chronic widespread pain (CWP) is associated with poor health-related quality of life (HRQoL). It is unclear whether pain itself is the cause of poor HRQoL or other factors play a role. We hypothesised that new onset of CWP was associated with poor physical and mental HRQoL but that psychosocial risk markers for CWP onset would explain this relationship. A prospective population-based survey measured pain and psychosocial status at baseline. Subjects free of CWP at baseline were followed up 15 months later, when pain status, threatening life events and HRQoL (SF-12) were assessed. The risk associated with the new onset of CWP and reporting poor SF12-MCS and SF12-PCS was quantified using multinomial logistic regression (relative risk ratios (RRRs) with 95% confidence intervals (95% CI)), adjusted for age and gender. 3000 subjects (77%) free of CWP at baseline participated at follow-up. 2650 subjects (88%) provided full SF-12 and pain data and formed the cohort for this analysis. 9.4% of subjects (n = 248) reported new CWP. New CWP was associated with an increased risk of having the poorest SF12-MCS (RRR = 2.3; 95% CI 1.6-3.2) and SF12-PCS (RRR= 8.0; 95% CI 5.4-11.8) scores. After adjusting for baseline psychosocial status, the relationship between CWP onset and SF12-MCS was attenuated (RRR = 1.2; 95% CI 0.8-1.8), although the association with SF12-PCS remained (RRR = 4.8% CI 3.1-7.47). New onset of CWP is associated with poor mental and physical HRQoL. However, the relationship with mental HRQoL is explained by psychosocial risk markers.
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Premorbid psychosocial factors are associated with poor health-related quality of life in subjects with new onset of chronic widespread pain : Results from the EPIFUND study
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Autor/in / Beteiligte Person: | NICHOLL, B. I ; MACFARLANE, G. J ; DAVIES, K. A ; MORRISS, R ; DICKENS, C ; MCBETH, J |
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Zeitschrift: | Pain (Amsterdam), Jg. 141 (2009), Heft 1-2, S. 119-126 |
Veröffentlichung: | Philadelphia, PA: Elsevier, 2009 |
Medientyp: | academicJournal |
Umfang: | print, 46 ref |
ISSN: | 0304-3959 (print) |
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