Smoking cessation and lung cancer risk in an Asian population: Findings from the Singapore Chinese Health Study
In: British journal of cancer, Jg. 103 (2010), Heft 7, S. 1093-1096
Online
academicJournal
- print, 1/4 p
Zugriff:
BACKGROUND: Smoking cessation is an important strategy for reducing the harmful effects of tobacco, particularly in the prevention of lung cancer; however, prospective data on the impact of smoking cessation on lung cancer risk in Asian populations are limited. METHODS: We studied a population-based cohort of Chinese men and women aged 45-74 years - participants of the Singapore Chinese Health Study, Information on smoking, lifestyle and dietary habits was collected at the time of recruitment in 1993 - 1998; and smoking status was assessed again at a second interview in 1999-2004 (mean Interval 5.8 years). Participants were followed up to 31 December 2007, and incident cases of lung cancer were ascertained by linkage with population-wide registries. RESULTS: Among 45 900 participants, there were 463 incident cases of lung cancer. Relative to current smokers, those who quit smoking subsequent to baseline assessment had a 28% decrease in the risk of lung cancer (adjusted hazard ratio (HR) 0.72; 95% CI (95% confidence interval): 0.53-0.98). The risk was less than half in ex-smokers who had quit before the first interview and maintained their status (HR 0.42; 95% CI: 0.32-0.56). CONCLUSIONS: Reduction in lung cancer incidence with smoking cessation in Asian populations is substantial and can be observed within a few years after quitting.
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Smoking cessation and lung cancer risk in an Asian population: Findings from the Singapore Chinese Health Study
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Autor/in / Beteiligte Person: | WONG, K.-Y ; SEOW, A ; KOH, W.-P ; SHANKAR, A ; LEE, H.-P ; YU, M. C |
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Zeitschrift: | British journal of cancer, Jg. 103 (2010), Heft 7, S. 1093-1096 |
Veröffentlichung: | Basingstoke: Nature Publishing Group, 2010 |
Medientyp: | academicJournal |
Umfang: | print, 1/4 p |
ISSN: | 0007-0920 (print) |
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