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Multipass dynamic MRI and pharmacokinetic modeling are used to estimate perfusion parameters of leaky capillaries. Curve fitting and nonblind deconvolution are the established methods to derive the perfusion estimates from the observed arterial input function (AIF) and tissue tracer concentration function. These nonblind methods are sensitive to errors in the AIF, measured in some nearby artery or estimated by multichannel blind deconvolution. Here, a single-channel blind deconvolution algorithm is presented, which only uses a single tissue tracer concentration function to estimate the corresponding AIF and tissue impulse response function. That way, many errors affecting these functions are reduced. The validity of the algorithm is supported by simulations and tests on real data from mouse. The corresponding nonblind and multichannel methods are also presented.

Titel:	Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI
Autor/in / Beteiligte Person:	TAXT, Torfinn ; JIRIK, Radovan ; BREKKE RYGH, Cecilie ; GRUNER, Renate ; BARTOS, Michal ; ANDERSEN, Erling ; CURRY, Fitz-Roy ; REED, Rolf K
Link:	Volltext View record from PASCAL Archive
Zeitschrift:	IEEE transactions on biomedical engineering, Jg. 59 (2012), Heft 4, S. 1012-1021
Veröffentlichung:	New York, NY: Institute of Electrical and Electronics Engineers, 2012
Medientyp:	academicJournal
Umfang:	print, 43 ref
ISSN:	0018-9294 (print)
Schlagwort:	Biomedical engineering Génie biomédical Sciences exactes et technologie Exact sciences and technology Sciences appliquees Applied sciences Telecommunications et theorie de l'information Telecommunications and information theory Théorie de l'information, du signal et des communications Information, signal and communications theory Théorie du signal et des communications Signal and communications theory Signal, bruit Signal, noise Détection, estimation, filtrage, égalisation, prédiction Detection, estimation, filtering, equalization, prediction Sciences biologiques et medicales Biological and medical sciences Sciences medicales Medical sciences Informatique, statistique et modelisations biomedicales Computerized, statistical medical data processing and models in biomedicine Aide à la décision médicale. Aide au diagnostic Medical management aid. Diagnosis aid Appareil circulatoire Circulatory system Aparato circulatorio Imagerie médicale Medical imagery Imaginería médica Vaisseau sanguin Blood vessel Vaso sanguíneo Artère Artery Arteria Canal multiple Multiple channel Canal múltiple Déconvolution aveugle Blind deconvolution Desconvolución ciega Estimation canal Channel estimation Estimación canal Estimation paramètre Parameter estimation Estimación parámetro Ingeniería biomédica Identification aveugle Blind identification Identificación ciega Imagerie RMN Nuclear magnetic resonance imaging Imaginería RMN Réponse impulsion Pulse response Respuesta impulsión Arterial input function (AIF) blind deconvolution dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) multichannel perfusion single channel
Sonstiges:	Nachgewiesen in: PASCAL Archive Sprachen: English Original Material: INIST-CNRS Document Type: Article File Description: text Language: English Author Affiliations: Department of Biomedicine, University of Bergen, Bergen 5007, Norway, and also with the Department of Radiology, Haukeland University Hospital, Bergen 5058, Norway ; Institute of Scientific Instruments, Academy of Sciences of the Czech Republic, 115 22 Prague, Czech Republic ; Department of Biomedical Engineering, Brno University of Technology, Bmo 601 90, Czech Republic ; Department of Biomedicine, University of Bergen, 5020 Bergen, Norway ; Department of Biomedicine and Department of Physics and Technology, University of Bergen, 5020 Bergen, Norway ; Department of Biomedical Engineering, Brno University of Technology, Brno 601 90, Czech Republic ; Department of Clinical Engineering, Haukeland University Hospital, Bergen 5058, Norway ; Department of Physiology and Membrane Biology, University of California, Davis, CA 95616, United States Rights: Copyright 2015 INIST-CNRS ; CC BY 4.0 ; Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS Notes: Public health. Hygiene-occupational medicine. Information processing ; Telecommunications and information theory

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Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI