Structure and function of Mycobacterium tuberculosis meso-diaminopimelic acid (DAP) biosynthetic enzymes
In: FEMS microbiology letters, Jg. 330 (2012), Heft 1, S. 10-16
Online
academicJournal
- print, 2 p.1/4
Zugriff:
Because of an increased emergence of resistance to current antitubercular drugs, there is a need for new antitubercular agents directed against novel targets. Diaminopimelic acid (DAP) biosynthetic enzymes are unique to bacteria and are absent in mammals and provide a rich source of essential targets for antitubercular chemotherapy. Herein, we review the structure and function of the mycobacterial DAP biosynthetic enzymes.
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Structure and function of Mycobacterium tuberculosis meso-diaminopimelic acid (DAP) biosynthetic enzymes
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Autor/in / Beteiligte Person: | USHA, Veeraraghavan ; LLOYD, Adrian J ; LOVERING, Andrew L ; BESRA, Gurdyal S |
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Zeitschrift: | FEMS microbiology letters, Jg. 330 (2012), Heft 1, S. 10-16 |
Veröffentlichung: | Oxford: Wiley-Blackwell, 2012 |
Medientyp: | academicJournal |
Umfang: | print, 2 p.1/4 |
ISSN: | 0378-1097 (print) |
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