The SDF-1/CXCR4 axis in stem cell preconditioning
In: Cardiovascular research, Jg. 94 (2012), Heft 3, S. 400-407
Online
academicJournal
- print, 137 ref
Zugriff:
We review the pivotal role of the stromal derived factor (SDF)-1 chemokine in tissue ischaemia and how it orchestrates the rapid revascularization of injured, ischaemic, and regenerating tissues via the CXC chemokine receptors CXCR4 and CXCR7. Furthermore, we discuss the effects of preconditioning (PC), which is a well-known protective phenomenon for tissue ischaemia. The positive effect of both hypoxic and acidic PC on progenitor cell therapeutic potential is reviewed, while stressing the role of the SDF-1/CXCR4 axis in this process.
Titel: |
The SDF-1/CXCR4 axis in stem cell preconditioning
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Autor/in / Beteiligte Person: | CENCIONI, Chiara ; CAPOGROSSI, Maurizio C ; NAPOLITANO, Monica |
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Zeitschrift: | Cardiovascular research, Jg. 94 (2012), Heft 3, S. 400-407 |
Veröffentlichung: | Oxford: Oxford University Press, 2012 |
Medientyp: | academicJournal |
Umfang: | print, 137 ref |
ISSN: | 0008-6363 (print) |
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