The Epidemiology and Aetiology of Infections in Children Admitted with Clinical Severe Pneumonia to a University Hospital in Rabat, Morocco
In: Journal of tropical pediatrics (1980), Jg. 60 (2014), Heft 4, S. 270-278
Online
academicJournal
- print, 26 ref
Zugriff:
Objectives: Scarce and limited epidemiological, clinical and microbiological data are available regarding paediatric respiratory tract infections in the Kingdom of Morocco, a middle-income country in northwestern Africa. The results of hospital-based surveillance aiming at describing the aetiology and epidemiology of respiratory distress among children <5 years of age are presented. Methods: Children admitted to the Hôpital d'Enfants de Rabat, Morocco, and meeting the World Health Organization clinical criteria for severe pneumonia were recruited over a period of 14 months and were thoroughly investigated to ascertain a definitive diagnosis. Results: In total, 700 children were recruited for the study. Most frequent clinical diagnoses included wheezing-related conditions (bronchitis/asthma, 46%; bronchiolitis, 15%), while typical bacterial pneumonia was infrequent (only 19% of the cases). Invasive bacterial disease detected by classical microbiology or molecular methods was also uncommon, affecting only 3.5% of the patients, and with an overall low detection of pneumococcal or Haemophilus influenzae type b disease. Conversely, coverage of respiratory viral detection in the nasopharynx was almost universal among cases (92%), with the three most frequent viruses detected being rhinovirus (53%), respiratory syncytial virus (18%) and adenovirus (17%). The overall case fatality rate (CFR) among recruited patients with a known outcome was 4.1% (28/690). Conclusions: In Morocco, the epidemiological profile of paediatric acute respiratory infections is markedly shifted towards wheezing-related diseases and thus resembles that of high-income countries. However, the high associated CFRs found in this study call for an improvement in preventive and clinical management strategies.
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The Epidemiology and Aetiology of Infections in Children Admitted with Clinical Severe Pneumonia to a University Hospital in Rabat, Morocco
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Autor/in / Beteiligte Person: | JROUNDI, Imane ; MAHRAOUI, Chafiq ; HAYES, Edward B ; ALVAREZ-MARTINEZ, Miriam J ; MUNOZ-ALMAGRO, Carmen ; RUIZ, Joaquim ; ALONSO, Pedro L ; BASSAT, Quique ; BENMESSAOUD, Rachid ; MORALEDA, Cinta ; TLIGUI, Houssain ; SEFFAR, Myriam ; KETTANI, Selma Cherif ; BADR SOUOUD, BENJELLOUN ; CHAACHO, Saad ; MAAROUFI, Abderrahman |
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Zeitschrift: | Journal of tropical pediatrics (1980), Jg. 60 (2014), Heft 4, S. 270-278 |
Veröffentlichung: | Oxford: Oxford University Press, 2014 |
Medientyp: | academicJournal |
Umfang: | print, 26 ref |
ISSN: | 0142-6338 (print) |
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