Decreased Ceftriaxone Susceptibility in Emerging (35B and 6C) and Persisting (19A) Streptococcus pneumoniae Serotypes in the United States, 2011-2012: Ceftaroline Remains Active In Vitro among β-Lactam Agents
In: Antimicrobial agents and chemotherapy, Jg. 58 (2014), Heft 8, S. 4923-4927
Online
academicJournal
- print, 21 ref
Zugriff:
Totals of 8.7% (103/1,190) and 21.0% (249/1,190) of the Streptococcus pneumoniae isolates recovered from specimens collected in the United States during the 2011-2012 AWARE (Assessing Worldwide Antimicrobial Resistance Evaluation) Surveillance Program were ceftriaxone nonsusceptible according to the CLSI (≤1 μg/ml for susceptible) and EUCAST (≤0.5 μg/ml for susceptible) criteria, respectively. Decreased susceptibility to ceftriaxone (MIC, 1 μg/ml) was frequently observed among serotypes 19A (51.4%; 128/249) and 35B (29.7%; 74/249), which were most often observed in the East South Central and South Atlantic U.S. Census regions. Ceftaroline (MIC50/90, 0.12/0.25 μg/ml) remained active (≥96.8% susceptible) when tested against these less susceptible isolates.
| Titel: |
Decreased Ceftriaxone Susceptibility in Emerging (35B and 6C) and Persisting (19A) Streptococcus pneumoniae Serotypes in the United States, 2011-2012: Ceftaroline Remains Active In Vitro among β-Lactam Agents
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| Autor/in / Beteiligte Person: | MENDES, Rodrigo E ; BIEK, Donald ; CRITCHLEY, Ian A ; FARRELL, David J ; SADER, Helio S ; JONES, Ronald N |
| Link: | |
| Zeitschrift: | Antimicrobial agents and chemotherapy, Jg. 58 (2014), Heft 8, S. 4923-4927 |
| Veröffentlichung: | Washington, DC: American Society for Microbiology, 2014 |
| Medientyp: | academicJournal |
| Umfang: | print, 21 ref |
| ISSN: | 0066-4804 (print) |
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