The bubble test : a new tool to improve the diagnosis of endometriosis
In: Human reproduction (Oxford. Print), Jg. 10 (1995), Heft 4, S. 923-926
Online
academicJournal
- print, 7 ref
Zugriff:
The objective of this study was to determine the clinical sensitivity and specificity of a bubbling phenomenon, including peritoneal surfaces, as a diagnostic test for endometriosis during laparoscopy. A prospectively controlled study of women with infertility of at least 1 year duration, who underwent laparoscopy, was conducted at a medical school-afffiliated private infertility centre and research foundation. The study included 48 prospectively enrolled female infertility patients who underwent laparoscopy. Of these, 32 were found to suffer from endometriosis (group A) and 16 control patients did not show any evidence of disease (group B). The study involved the irrigation of the posterior cul-de-sac with short bursts of either saline or lactated Ringer's solution, utilizing a standard laparoscopic aspiration/irrigation system, and the subsequent observation for an excessive soap-like bubbling phenomenon (positive bubble test) in association with endometriosis. All 32 endometriosis patients (group A) demonstrated a positive bubble test. In contrast, only two oe the 16 control patients (group B) were positive (P=0.00242, Fisher's exact test; odds ratio, 8.000). A positive bubble test during laparoscopy was thus 100% sensitive and 88% specific for the diagnosis of endometriosis by laparoscopy, resulting in positive and negative predictive values of 94 and 100% respectively. Since the literature provides considerable evidence that the diagnosis of endometriosis during laparoscopy is frequently missed, a positive bubble test during laparoscopy therefore may be considered a reason to search further (possibly with biopsies) for endometriosis in the absence of obviously visible disease. If confirmed, a positive bubble test could then become an even more accurate single diagnostic test for endometriosis than laparoscopy.
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The bubble test : a new tool to improve the diagnosis of endometriosis
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Autor/in / Beteiligte Person: | GLEICHER, N ; KARANDE, V ; RABIN, D ; DUDKIEWICZ, A ; PRATT, D |
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Zeitschrift: | Human reproduction (Oxford. Print), Jg. 10 (1995), Heft 4, S. 923-926 |
Veröffentlichung: | Oxford: Oxford University Press, 1995 |
Medientyp: | academicJournal |
Umfang: | print, 7 ref |
ISSN: | 0268-1161 (print) |
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