The Haemophilus influenzae adenylate cyclase gene : cloning, sequence, and essential role in competence
In: Journal of bacteriology, Jg. 175 (1993), Heft 22, S. 7142-7149
Online
academicJournal
- print, 40 ref
Zugriff:
Competence for transformation in Haemophius influenzae is stimulated by cyclic AMP (cAMP) and requires the cAMP-dependent catabolite regulatory protein CRP. Thus, understanding the control of competence will require understanding how cAMP levels are regulated. As a first step, we have cloned the H. influenzae adenylate cyclase gene (cya) by complementing the Lac- phenotype of Δcya Escherichia coli. Its sequence specifies an 843-amino-acid protein which has significant identity to other known bacterial adenylate cyclases (41 to 43% and 61% identical to the cya genes of enteric bacteria and of Pasteurella multocida, respectively).
Titel: |
The Haemophilus influenzae adenylate cyclase gene : cloning, sequence, and essential role in competence
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Autor/in / Beteiligte Person: | DOROCICZ, I. R ; WILLIAMS, P. M ; REDFIELD, R. J |
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Zeitschrift: | Journal of bacteriology, Jg. 175 (1993), Heft 22, S. 7142-7149 |
Veröffentlichung: | Washington, DC: American Society for Microbiology, 1993 |
Medientyp: | academicJournal |
Umfang: | print, 40 ref |
ISSN: | 0021-9193 (print) |
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