Natural product chemistry. CLX: [1] Synthesis of 8-, 9-, 10- and 11-methylacronycines to improve the cytostatic activity of acronycine
In: Journal of heterocyclic chemistry, Jg. 30 (1993), Heft 6, S. 1469-1476
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Zugriff:
With the help of drug design, 8-, 9-, 10- and 11-methylacronycines (24, 25, 26 and 27) have been selected and synthesised to improve the cytostatic potency of acronycine (31). The condensation of phloro- glucinol with 6-methylanthranilic acid gave 7-hydroxy-1,9-dimethyl- dibenzo[b,j][1,7]phenanthroline-8,14(5H,13H)-dione (32) as the main product.
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Natural product chemistry. CLX: [1] Synthesis of 8-, 9-, 10- and 11-methylacronycines to improve the cytostatic activity of acronycine
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Autor/in / Beteiligte Person: | REISCH, J ; DZIEMBA, P ; ADAM, T |
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Zeitschrift: | Journal of heterocyclic chemistry, Jg. 30 (1993), Heft 6, S. 1469-1476 |
Veröffentlichung: | Odessa, FL: HeteroCorporation, 1993 |
Medientyp: | academicJournal |
Umfang: | print, |
ISSN: | 0022-152X (print) |
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