Fat emulsions for parenteral nutrition. IV: Lipofundin MCT/LCT regimens for total parenteral nutrition (TPN) with high electrolyte load
In: International journal of pharmaceutics, Jg. 107 (1994), Heft 2, S. 121-132
academicJournal
- print, 8 ref
Zugriff:
The stability of TPN regimens with high electrolyte load based on the emulsions Lipofundin MCT/LCT and Intralipid was investigated. The regimens were of identical composition containing 66.7 mmol/l monovalent ions and 6.7 mmol/l divalent ions (3.4 mmol Ca2+, 3.3 mmol other divalent ions such as Mg2+). Stability was monitored by microscopy, Coulter counter, photon correlation spectroscopy (PCS) and laser diffractometry. Zeta potential measurements were performed by laser Doppler anemometry (LDA). The Lipofundin regimen was regarded as being stable for 7 days of storage, the Intralipid regimen for at least 2 days but not 7 days. The storage time was limited due to visible heavy creaming and the increased numbers of particles >4 μm.
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Fat emulsions for parenteral nutrition. IV: Lipofundin MCT/LCT regimens for total parenteral nutrition (TPN) with high electrolyte load
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Autor/in / Beteiligte Person: | MÜLLER, R. H ; HEINEMANN, S |
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Zeitschrift: | International journal of pharmaceutics, Jg. 107 (1994), Heft 2, S. 121-132 |
Veröffentlichung: | Amsterdam: Elsevier, 1994 |
Medientyp: | academicJournal |
Umfang: | print, 8 ref |
ISSN: | 0378-5173 (print) |
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