High incidence of monoclonal EBV episomes in Hodgkin's disease and anaplastic large-cell KI-1-positive lymphomas in HIV-1-positive patients
In: International journal of cancer, Jg. 54 (1993), Heft 1, S. 53-59
Online
academicJournal
- print, 1 p
Zugriff:
A series of selected lymphoid malignancies (LMs) occurring in Italian HIV-I-infected (HIV+) patients, principally intravenous drug users, was investigated. In addition to small non-cleaved-cell (SNCC) and large-cell immunoblastic (LCI) non-Hodgkin's lymphomas (NHLs), a relatively high occurrence of anaplastic large-cell Ki-I-positive (ALC Ki-I+) lymphomas and Hodgkin's disease (HD) was observed, at variance with other reported series of HIV+ patients. Combined results of in situ hybridization and Southern-blot analyses, in conjunction with immunohistochemical detection of Epstein-Barr virus (EBV)-encoded latent membrane protein-I (LMP-I), showed an almost complete association of ALC Ki-I+ lymphomas and HD cases with EBV.
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High incidence of monoclonal EBV episomes in Hodgkin's disease and anaplastic large-cell KI-1-positive lymphomas in HIV-1-positive patients
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Autor/in / Beteiligte Person: | BOIOCCHI, M ; DE RE, V ; GLOGHINI, A ; VACCHER, E ; DOLCETTI, R ; MARZOTTO, A ; BERTOLA, G ; CARBONE, A |
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Zeitschrift: | International journal of cancer, Jg. 54 (1993), Heft 1, S. 53-59 |
Veröffentlichung: | New York, NY: Wiley-Liss, 1993 |
Medientyp: | academicJournal |
Umfang: | print, 1 p |
ISSN: | 0020-7136 (print) |
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