Calcium influx mediated by the Escherichia coli heat-stable enterotoxin B (STB)
In: Proceedings of the National Academy of Sciences of the United States of America, Jg. 90 (1993), Heft 8, S. 3202-3206
Online
academicJournal
- print, 41 ref
Zugriff:
The heat-stable enterotoxin B (STB) of Escherichia coli is a 48-amino acid extracellular peptide that induces rapid fluid accumulation in animal intestinal models. Unlike other E. coli enterotoxins that elicit cAMP or cGMP responses in the gut [heat-labile toxin (LT) and heat-stable toxin A (STA), respectively], STB induces fluid loss by an undefined mechanism that is independent of cyclic nucleotide elevation. Here we studied the effects of STB on intracellular calcium concentration ([Ca2+]i), another known mediator of intestinal ion and fluid movement.
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Calcium influx mediated by the Escherichia coli heat-stable enterotoxin B (STB)
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Autor/in / Beteiligte Person: | DREYFUS, L. A ; HARVILLE, B ; HOWARD, D. E ; RADWAN, SHABAN ; BEATTY, D. M ; MORRIS, S. J |
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Zeitschrift: | Proceedings of the National Academy of Sciences of the United States of America, Jg. 90 (1993), Heft 8, S. 3202-3206 |
Veröffentlichung: | Washington, DC: National Academy of Sciences of the United States of America, 1993 |
Medientyp: | academicJournal |
Umfang: | print, 41 ref |
ISSN: | 0027-8424 (print) |
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