Cim : an MHC class II-linked allelism affecting the antigenicity of a classical class I molecule for T lymphocytes
In: Immunogenetics (New York, NY), Jg. 34 (1991), Heft 3, S. 157-163
Online
academicJournal
- print, 22 ref
Zugriff:
Two alleles at the major histocompatibility complex (MHC)-linked locus cim determine gain and loss changes in the rat RT1.Aa class I molecule which affect its structure both as an alloantigen and as a restriction element. Alleles at the cim locus also influence the post-translational modification of RT1.Aa. These effects may reflect the participation of the cim gene product in the processes of peptide loading or assembly of RT1.Aa. In this study we have used the discriminating RT1.Aa-specific monoclonal antibody JY3/84, as well as cytotoxic T cells raised in appropriate combinations, to determine the cim allelles of eight haplotypes in 15 independent inbred strains of rat.
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Cim : an MHC class II-linked allelism affecting the antigenicity of a classical class I molecule for T lymphocytes
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Autor/in / Beteiligte Person: | LIVINGSTONE, A. M ; POWIS, S. J ; GÜNTHER, E ; CRAMER, D. V ; HOWARD, J. C ; BUTCHER, G. W |
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Zeitschrift: | Immunogenetics (New York, NY), Jg. 34 (1991), Heft 3, S. 157-163 |
Veröffentlichung: | Berlin; Heidelberg: Springer, 1991 |
Medientyp: | academicJournal |
Umfang: | print, 22 ref |
ISSN: | 0093-7711 (print) |
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