Responsiveness of bone marrow erythroid progenitors (CFU-E and BFU-E) to recombinant human erythropoietin (rh-Ep) in vitro in multiple myeloma
In: British journal of haematology, Jg. 81 (1992), Heft 4, S. 463-469
academicJournal
- print, 1 p
Zugriff:
The responsiveness of bone marrow erythroid progenitors (CFU-E and BFU-E) to recombinant human erythropoietin (rh-Ep) was investigated in vitro in 21 patients with multiple myeloma to assess the clinical usefulness of rh-Ep in this disease. CFU-E and BFU-E assays were performed by methylcellulose culture methods. The myeloma patients were divided into two groups according to the percentage of plasma cells in the bone marrow (over 50%and under 50%). Among the patients with few plasma cells, some revealed normal CFU-E and BFU-E growth at 2 units of rh-Ep, and no further increase was observed even with an increasing dose of rh-Ep.
Titel: |
Responsiveness of bone marrow erythroid progenitors (CFU-E and BFU-E) to recombinant human erythropoietin (rh-Ep) in vitro in multiple myeloma
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Autor/in / Beteiligte Person: | AOKI, I ; NISHIJIMA, K ; HOMORI, M ; NAKAHARA, K ; HIGASHI, K ; ISIKAWA, K |
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Zeitschrift: | British journal of haematology, Jg. 81 (1992), Heft 4, S. 463-469 |
Veröffentlichung: | Oxford: Blackwell, 1992 |
Medientyp: | academicJournal |
Umfang: | print, 1 p |
ISSN: | 0007-1048 (print) |
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