Molecular cloning of the cDNA for an MDCK cell Na+- and Cl--dependent taurine transporter that is regulated by hypertonicity
In: Proceedings of the National Academy of Sciences of the United States of America, Jg. 89 (1992), Heft 17, S. 8230-8234
Online
academicJournal
- print, 27 ref
Zugriff:
Cells in the hypersonic renal medulla maintain their intracellular ion concentration at isotonic levels, despite much higher concentrations of extracellular electrolytes, by accumulating high concentrations of nonperturbing small organic solutes termed osmolytes. Taurine has been idenfied as a nonperturbing osmolyte in the renal medulla and Madin-Darby canine kidney (MDCK) cells. In hypersonic medium, the increased accumulation of taurine in MDCK cells is the result of increased activity of a Na+- and Cl--dependent taurine transporter.
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Molecular cloning of the cDNA for an MDCK cell Na+- and Cl--dependent taurine transporter that is regulated by hypertonicity
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Autor/in / Beteiligte Person: | UCHIDA, S ; MOO KWON, H ; YAMAUCHI, A ; PRESTON, A. S ; MARUMO, F ; HANDLER, J. S |
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Zeitschrift: | Proceedings of the National Academy of Sciences of the United States of America, Jg. 89 (1992), Heft 17, S. 8230-8234 |
Veröffentlichung: | Washington, DC: National Academy of Sciences of the United States of America, 1992 |
Medientyp: | academicJournal |
Umfang: | print, 27 ref |
ISSN: | 0027-8424 (print) |
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