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Laparoscopic Versus Open Major Hepatectomy for HCC Hepatectomy for Hepatocellular Carcinoma (AP-LAPO)

Health and Medicine Research Fund ; Kelvin K.C. Ng, Professor
In: Bray F, Ferlay J, Soerjomataram Sgel RL, Torre LA, Jemal A. Global cancer statts 2018: GLOBOCAN estates of cence and mortaly worldwe for 36 cancers 185 countrs. CA Cancer J Cl. 2018 Nov;68(6):394-424. do 10.3322/caac.21492. Epub 2018 Sep 12. Erratum : CA Cancer J Cl. 2020 Jul;70(4):313. European Assoctn for the Study of the Ler. Electron address: easloffe@easloffe.eu; European Assoctn for the Study of the Ler. EASL Clal Practe Gueles: Management of hepatocellular carcoma. J Hepatol. 2018 Jul;69(1):182-236. do 10.1016/j.jhep.2018.03.019. Epub 2018 Apr 5. No abstract avaable. Erratum : J Hepatol. 2019 Apr;70(4):817. Hebach JK, Kul LM, Fn RS, Sl CB, Abecass MM, Roberts LR, Zhu AX, Murad MH, Marrero JA. AASLD gueles for the treatment of hepatocellular carcoma. Hepatology. 2018 Jan;67(1):358-380. do 10.1002/hep.29086. No abstract avaable. Vogel A, Cervantes A, Chau Danle B, Llovet JM, Meyer T, Nault JC, Neumann U, Rke J, Sangro B, Schmacher P, Verslype C, Zech CJ, Arnold D, MartellE; ESMO Gueles Commtee. Hepatocellular carcoma: ESMO Clal Practe Gueles for dgnos, treatment and follow-up. Ann Oncol. 2018 Oct 1;29(Suppl 4):238-255. do 10.1093/annonc/mdy308. No abstract avaable. Erratum : Ann Oncol. 2019 May 1;30(5):871-873. Ann Oncol. 2022 Jun;33(6):666. Ng KK, Vauthey JN, Pawl TM, Lauwers GY, Regbeau JM, BelghJ, a Yamaoka Y, Curley SA, Nagorney DM, Ng , Fan ST, Poon RT; ternatnal Cooperate Study Group on Hepatocellular Carcoma. hepat resectn for large or multodular hepatocellular carcoma justd? Results from a multstutnal database. Ann Surg Oncol. 2005 May;12(5):364-73. do 10.1245/ASO.2005.06.004. Epub 2005 Mar 31. Hao S, Fan P, Chen S, Tu C, Wan C. Anterr approach to prove the long-term outcome patnts wh large-se hepatocellular carcoma havg ler resectn. J Surg Oncol. 2016 Dec;114(7):872-878. do 10.1002/jso.24433. Epub 2016 Sep 16. Lee KF, Cheung YS, Wong J, Chong CC, Wong JS, LaPB. Randomed clal trl of open hepatectomy wh or whout termtent Prgle manoeuvre. Br J Surg. 2012 Sep;99(9):1203-9. do 10.1002/bjs.8863. Epub 2012 Jul 24. Ng KKC, Chok KSH, Chan ACY, Cheung TT, Wong TCL, Fung JYY, Yuen J, Poon RTP, Fan ST, Lo CM. Randomed clal trl of hepat resectn versus radfrequency ablatn for early-stage hepatocellular carcoma. Br J Surg. 2017 Dec;104(13):1775-1784. do 10.1002/bjs.10677. Epub 2017 Nov 1. Ng KK, Cheung TT, Pang HH, Wong TC, DaJW, Ma KW, She WH, Kotewall CN, Lo CM. A spld predtn model for early trahepat recurrence after hepatectomy for patnts wh unobar hepatocellular carcoma whout macroscop vascular vasn: An platn for adjuvant therapy and postoperate survelance. Surg Oncol. 2019 Sep;30:6-12. do 10.1016/j.suronc.2019.05.017. Epub 2019 May 22. Jarnag WR, Delman K, Kooby D, Mastores S, Zager J, Brennan MF, Blumgart LH, Federoff H, Fong Y. Neoadjuvant terleuk-12 munogene therapy protects agast cancer recurrence after ler resectn an anal model. Ann Surg. 2000 May;231(5):762-71. do 10.1097/00000658-200005000-00017. Halls MC, BerardG, CrnF, Barkhatov L, Laas P, Harr S, D'Hondt M, Rotellar F, Dagher AldrhettL, TroR Edw B, Abu Hal M. Development and valatn of a dfulty score to predt traoperate complatns durg laparoscop ler resectn. Br J Surg. 2018 Aug;105(9):1182-1191. do 10.1002/bjs.10821. Epub 2018 May 8. Chen K, Pan Y, Hu GY, Maher H, Zheng XY, Yan JF. Laparoscop Versus Open Major Hepatectomy for Hepatocellular Carcoma: A Meta-Analys. Surg Laparosc Endosc Percutan Tech. 2018 Oct;28(5):267-274. do 10.1097/SLE.0000000000000567. Xu HW, L F, LHY, WeYG, LB. Outcomes followg laparoscop versus open major hepatectomy for hepatocellular carcoma patnts wh crhos: a propensy score-matched analys. Surg Endosc. 2018 Feb;32(2):712-719. do 10.1007/s00464-017-5727-2. Epub 2017 Jul 19. Delvecch A, Contch M, RattF, GellM, AnellFM, Laurent A, ValGC, MagtrP, AssatG, FellE, WakabayashT, Pessaux P, PrdT, DBenedetto F, de'Angel N, Breno-Delgado J, Adam R, CherquD, AldrhettL, Memeo R. Laparoscop major hepatectomy for hepatocellular carcoma elderly patnts: a multentr propensy score-based analys. Surg Endosc. 2021 Jul;35(7):3642-3652. do 10.1007/s00464-020-07843-7. Epub 2020 Aug 3. Yoon Y K KH, Kang SH, K WJ, Sh MH, Lee SK, Jung DH, Park GC, Ahn CS, Moon DB, Ha TY, Song GW, Hwang S, Lee SG. Pure Laparoscop Versus Open Rht Hepatectomy for Hepatocellular Carcoma Patnts Wh Crhos: A Propensy Score Matched Analys. Ann Surg. 2017 May;265(5):856-863. do 10.1097/SLA.0000000000002072. Marrero JA, Kul LM, Sl CB, Zhu AX, Fn RS, Abecass MM, Roberts LR, Hebach JK. Dgnos, Stagg, and Management of Hepatocellular Carcoma: 2018 Practe Guance by the Ameran Assoctn for the Study of Ler Deases. Hepatology. 2018 Aug;68(2):723-750. do 10.1002/hep.29913. No abstract avaable. Abu Hal M, AldrhettL, Dagher Edw B, TroR Alhanov R, AroorS, BellG, Besselk M, Breno J, Gayet B, D'Hondt M, Lesurtel M, Menon K, Lodge P, Rotellar F, Santoyo J, Scatton O, Soubrane O, Sutclfe R, Van Dam R, Whe S, Halls MC, CrnF, Van der Poel M, C R, Barkhatov L, Gomez-Luque Y, Ocana-Garc S, Cook A, Buell J, Clavn PA, Derven C, FusaG, Geller D, Lang H, Prrose J, Taylor M, Van Gul T, WakabayashG, Asbun H, CherquD. The Southampton Consensus Gueles for Laparoscop Ler Surgery: From datn to plementatn. Ann Surg. 2018 Jul;268(1):11-18. do 10.1097/SLA.0000000000002524. C R, Gomez-Luque Ocana S, CrnF, Halls M, Breno J, Okuda Y, TroR, Rotellar F, Soubrane O, Abu Hal M. A Systemat Revw and Meta-Analys Comparg the Short- and Long-Term Outcomes for Laparoscop and Open Ler Resectns for Hepatocellular Carcoma: Updated Results from the European Gueles Meetg on Laparoscop Ler Surgery, Southampton, UK, 2017. Ann Surg Oncol. 2019 Jan;26(1):252-263. do 10.1245/s10434-018-6926-3. Epub 2018 Nov 2. Munteanu A, Munteanu D, ncu M, Lupan Samasca G, Aldea C, Mocan T, ncu C. Assessg munologal surgal stress markers patnts undergog deste surgery for pancreat, hepat and gastr tumors. J BUON. 2018 Nov-Dec;23(6):1655. European Assoctn For The Study Of The Ler; European Organatn For Research And Treatment Of Cancer. EASL-EORTC clal practe gueles: management of hepatocellular carcoma. J Hepatol. 2012 Apr;56(4):908-43. do 10.1016/j.jhep.2011.12.001. No abstract avaable. Erratum : J Hepatol. 2012 Jun;56(6):1430. van der Poel MJ, Besselk MG, CrnF, Armstrong T, Takhar AS, van Dren S, Prrose JN, Pearce NW, Abu Hal M. Outcome and Learng Curve 159 Consecute Patnts Undergog Total Laparoscop Hemepatectomy. JAMA Surg. 2016 Oct 1;151(10):923-928. do 10.1001/jamasurg.2016.1655. L CL, Fan ST, Cheung ST, Lo CM, Ng , Wong J. Anterr approach versus conventnal approach rht hepat resectn for large hepatocellular carcoma: a prospecte randomed controlled study. Ann Surg. 2006 Aug;244(2):194-203. do 10.1097/01.sla.0000225095.18754.45. Ng KKC, Cheng NMY, Huang J, Lo M, Chong CCN, Lee KF, Wong J, Cheung SYS, Lok HT, Fung AKY, Wong GLH, Wong VWS, LaPBS. Development and valatn of a novel nomogram predtg 10-year actual surval after curate hepatectomy for hepatocellular carcoma. Surgeon. 2021 Dec;19(6):329-337. do 10.1016/j.surge.2020.11.013. Epub 2021 Jan 8. Ddo D, Demartes N, Clavn PA. Classatn of surgal complatns: a new proposal wh evaluatn a cohort of 6336 patnts and results of a survey. Ann Surg. 2004 Aug;240(2):205-13. do 10.1097/01.sla.0000133083.54934.ae. Bad JM, Ayton LC, Evans TJ, Carpenter AJ, Nawfal G, Kderman H, Zografos G, Uemoto S, Cohen J, Hab NA. System cytoke response to hepat resectns under total vascular exclusn. Eur J Surg. 1998 Mar;164(3):185-90. do 10.1080/110241598750004625. anaga T, SuzukH. Perperate allogen blood transfusn and serum levels of munosuppresse ac prote patnts undergog resectn of colorectal carcoma. D D Sc 1999 Aug;44(8):1601-4. do 10.1023/a:1026619111897. arashT, Tobe T, KuramochH, Akakura K, hawa T, Hamano S, SuzukN, Furuya Y, o H. Serum munosuppresse ac prote as a potent prognost factor for patnts wh metastat renal cell carcoma. Jpn J Cl Oncol. 2001 Jan;31(1):13-7. do 10.1093/jjco/hye004. Shada M, Takenaka K, Kawahara N, Kajama K, Yamamoto K, Shabe K, NhakT, Yanaga K, SugachK. Surgal treatment strategy for patnts wh stage hepatocellular carcoma. Surgery. 1996 May;119(5):517-22. do 10.1016/s0039-6060(96)80260-1. Donner A. Approaches to sample se estatn the desn of clal trls--a revw. Stat Med. 1984 Jul-Sep;3(3):199-214. do 10.1002/s.4780030302. Erratum : Stat Med 1990 Oct;9(10):1228. Asia-Pacific Multi-Centre Randomized Trial of Laparoscopic Versus Open Major Hepatectomy for Hepatocellular Carcinoma (AP-LAPO Trial)
Online report

Titel:
Laparoscopic Versus Open Major Hepatectomy for HCC Hepatectomy for Hepatocellular Carcinoma (AP-LAPO)
Autor/in / Beteiligte Person: Health and Medicine Research Fund ; Kelvin K.C. Ng, Professor
Link:
Quelle: Bray F, Ferlay J, Soerjomataram Sgel RL, Torre LA, Jemal A. Global cancer statts 2018: GLOBOCAN estates of cence and mortaly worldwe for 36 cancers 185 countrs. CA Cancer J Cl. 2018 Nov;68(6):394-424. do 10.3322/caac.21492. Epub 2018 Sep 12. Erratum : CA Cancer J Cl. 2020 Jul;70(4):313. European Assoctn for the Study of the Ler. Electron address: easloffe@easloffe.eu; European Assoctn for the Study of the Ler. EASL Clal Practe Gueles: Management of hepatocellular carcoma. J Hepatol. 2018 Jul;69(1):182-236. do 10.1016/j.jhep.2018.03.019. Epub 2018 Apr 5. No abstract avaable. Erratum : J Hepatol. 2019 Apr;70(4):817. Hebach JK, Kul LM, Fn RS, Sl CB, Abecass MM, Roberts LR, Zhu AX, Murad MH, Marrero JA. AASLD gueles for the treatment of hepatocellular carcoma. Hepatology. 2018 Jan;67(1):358-380. do 10.1002/hep.29086. No abstract avaable. Vogel A, Cervantes A, Chau Danle B, Llovet JM, Meyer T, Nault JC, Neumann U, Rke J, Sangro B, Schmacher P, Verslype C, Zech CJ, Arnold D, MartellE; ESMO Gueles Commtee. Hepatocellular carcoma: ESMO Clal Practe Gueles for dgnos, treatment and follow-up. Ann Oncol. 2018 Oct 1;29(Suppl 4):238-255. do 10.1093/annonc/mdy308. No abstract avaable. Erratum : Ann Oncol. 2019 May 1;30(5):871-873. Ann Oncol. 2022 Jun;33(6):666. Ng KK, Vauthey JN, Pawl TM, Lauwers GY, Regbeau JM, BelghJ, a Yamaoka Y, Curley SA, Nagorney DM, Ng , Fan ST, Poon RT; ternatnal Cooperate Study Group on Hepatocellular Carcoma. hepat resectn for large or multodular hepatocellular carcoma justd? Results from a multstutnal database. Ann Surg Oncol. 2005 May;12(5):364-73. do 10.1245/ASO.2005.06.004. Epub 2005 Mar 31. Hao S, Fan P, Chen S, Tu C, Wan C. Anterr approach to prove the long-term outcome patnts wh large-se hepatocellular carcoma havg ler resectn. J Surg Oncol. 2016 Dec;114(7):872-878. do 10.1002/jso.24433. Epub 2016 Sep 16. Lee KF, Cheung YS, Wong J, Chong CC, Wong JS, LaPB. Randomed clal trl of open hepatectomy wh or whout termtent Prgle manoeuvre. Br J Surg. 2012 Sep;99(9):1203-9. do 10.1002/bjs.8863. Epub 2012 Jul 24. Ng KKC, Chok KSH, Chan ACY, Cheung TT, Wong TCL, Fung JYY, Yuen J, Poon RTP, Fan ST, Lo CM. Randomed clal trl of hepat resectn versus radfrequency ablatn for early-stage hepatocellular carcoma. Br J Surg. 2017 Dec;104(13):1775-1784. do 10.1002/bjs.10677. Epub 2017 Nov 1. Ng KK, Cheung TT, Pang HH, Wong TC, DaJW, Ma KW, She WH, Kotewall CN, Lo CM. A spld predtn model for early trahepat recurrence after hepatectomy for patnts wh unobar hepatocellular carcoma whout macroscop vascular vasn: An platn for adjuvant therapy and postoperate survelance. Surg Oncol. 2019 Sep;30:6-12. do 10.1016/j.suronc.2019.05.017. Epub 2019 May 22. Jarnag WR, Delman K, Kooby D, Mastores S, Zager J, Brennan MF, Blumgart LH, Federoff H, Fong Y. Neoadjuvant terleuk-12 munogene therapy protects agast cancer recurrence after ler resectn an anal model. Ann Surg. 2000 May;231(5):762-71. do 10.1097/00000658-200005000-00017. Halls MC, BerardG, CrnF, Barkhatov L, Laas P, Harr S, D'Hondt M, Rotellar F, Dagher AldrhettL, TroR Edw B, Abu Hal M. Development and valatn of a dfulty score to predt traoperate complatns durg laparoscop ler resectn. Br J Surg. 2018 Aug;105(9):1182-1191. do 10.1002/bjs.10821. Epub 2018 May 8. Chen K, Pan Y, Hu GY, Maher H, Zheng XY, Yan JF. Laparoscop Versus Open Major Hepatectomy for Hepatocellular Carcoma: A Meta-Analys. Surg Laparosc Endosc Percutan Tech. 2018 Oct;28(5):267-274. do 10.1097/SLE.0000000000000567. Xu HW, L F, LHY, WeYG, LB. Outcomes followg laparoscop versus open major hepatectomy for hepatocellular carcoma patnts wh crhos: a propensy score-matched analys. Surg Endosc. 2018 Feb;32(2):712-719. do 10.1007/s00464-017-5727-2. Epub 2017 Jul 19. Delvecch A, Contch M, RattF, GellM, AnellFM, Laurent A, ValGC, MagtrP, AssatG, FellE, WakabayashT, Pessaux P, PrdT, DBenedetto F, de'Angel N, Breno-Delgado J, Adam R, CherquD, AldrhettL, Memeo R. Laparoscop major hepatectomy for hepatocellular carcoma elderly patnts: a multentr propensy score-based analys. Surg Endosc. 2021 Jul;35(7):3642-3652. do 10.1007/s00464-020-07843-7. Epub 2020 Aug 3. Yoon Y K KH, Kang SH, K WJ, Sh MH, Lee SK, Jung DH, Park GC, Ahn CS, Moon DB, Ha TY, Song GW, Hwang S, Lee SG. Pure Laparoscop Versus Open Rht Hepatectomy for Hepatocellular Carcoma Patnts Wh Crhos: A Propensy Score Matched Analys. Ann Surg. 2017 May;265(5):856-863. do 10.1097/SLA.0000000000002072. Marrero JA, Kul LM, Sl CB, Zhu AX, Fn RS, Abecass MM, Roberts LR, Hebach JK. Dgnos, Stagg, and Management of Hepatocellular Carcoma: 2018 Practe Guance by the Ameran Assoctn for the Study of Ler Deases. Hepatology. 2018 Aug;68(2):723-750. do 10.1002/hep.29913. No abstract avaable. Abu Hal M, AldrhettL, Dagher Edw B, TroR Alhanov R, AroorS, BellG, Besselk M, Breno J, Gayet B, D'Hondt M, Lesurtel M, Menon K, Lodge P, Rotellar F, Santoyo J, Scatton O, Soubrane O, Sutclfe R, Van Dam R, Whe S, Halls MC, CrnF, Van der Poel M, C R, Barkhatov L, Gomez-Luque Y, Ocana-Garc S, Cook A, Buell J, Clavn PA, Derven C, FusaG, Geller D, Lang H, Prrose J, Taylor M, Van Gul T, WakabayashG, Asbun H, CherquD. The Southampton Consensus Gueles for Laparoscop Ler Surgery: From datn to plementatn. Ann Surg. 2018 Jul;268(1):11-18. do 10.1097/SLA.0000000000002524. C R, Gomez-Luque Ocana S, CrnF, Halls M, Breno J, Okuda Y, TroR, Rotellar F, Soubrane O, Abu Hal M. A Systemat Revw and Meta-Analys Comparg the Short- and Long-Term Outcomes for Laparoscop and Open Ler Resectns for Hepatocellular Carcoma: Updated Results from the European Gueles Meetg on Laparoscop Ler Surgery, Southampton, UK, 2017. Ann Surg Oncol. 2019 Jan;26(1):252-263. do 10.1245/s10434-018-6926-3. Epub 2018 Nov 2. Munteanu A, Munteanu D, ncu M, Lupan Samasca G, Aldea C, Mocan T, ncu C. Assessg munologal surgal stress markers patnts undergog deste surgery for pancreat, hepat and gastr tumors. J BUON. 2018 Nov-Dec;23(6):1655. European Assoctn For The Study Of The Ler; European Organatn For Research And Treatment Of Cancer. EASL-EORTC clal practe gueles: management of hepatocellular carcoma. J Hepatol. 2012 Apr;56(4):908-43. do 10.1016/j.jhep.2011.12.001. No abstract avaable. Erratum : J Hepatol. 2012 Jun;56(6):1430. van der Poel MJ, Besselk MG, CrnF, Armstrong T, Takhar AS, van Dren S, Prrose JN, Pearce NW, Abu Hal M. Outcome and Learng Curve 159 Consecute Patnts Undergog Total Laparoscop Hemepatectomy. JAMA Surg. 2016 Oct 1;151(10):923-928. do 10.1001/jamasurg.2016.1655. L CL, Fan ST, Cheung ST, Lo CM, Ng , Wong J. Anterr approach versus conventnal approach rht hepat resectn for large hepatocellular carcoma: a prospecte randomed controlled study. Ann Surg. 2006 Aug;244(2):194-203. do 10.1097/01.sla.0000225095.18754.45. Ng KKC, Cheng NMY, Huang J, Lo M, Chong CCN, Lee KF, Wong J, Cheung SYS, Lok HT, Fung AKY, Wong GLH, Wong VWS, LaPBS. Development and valatn of a novel nomogram predtg 10-year actual surval after curate hepatectomy for hepatocellular carcoma. Surgeon. 2021 Dec;19(6):329-337. do 10.1016/j.surge.2020.11.013. Epub 2021 Jan 8. Ddo D, Demartes N, Clavn PA. Classatn of surgal complatns: a new proposal wh evaluatn a cohort of 6336 patnts and results of a survey. Ann Surg. 2004 Aug;240(2):205-13. do 10.1097/01.sla.0000133083.54934.ae. Bad JM, Ayton LC, Evans TJ, Carpenter AJ, Nawfal G, Kderman H, Zografos G, Uemoto S, Cohen J, Hab NA. System cytoke response to hepat resectns under total vascular exclusn. Eur J Surg. 1998 Mar;164(3):185-90. do 10.1080/110241598750004625. anaga T, SuzukH. Perperate allogen blood transfusn and serum levels of munosuppresse ac prote patnts undergog resectn of colorectal carcoma. D D Sc 1999 Aug;44(8):1601-4. do 10.1023/a:1026619111897. arashT, Tobe T, KuramochH, Akakura K, hawa T, Hamano S, SuzukN, Furuya Y, o H. Serum munosuppresse ac prote as a potent prognost factor for patnts wh metastat renal cell carcoma. Jpn J Cl Oncol. 2001 Jan;31(1):13-7. do 10.1093/jjco/hye004. Shada M, Takenaka K, Kawahara N, Kajama K, Yamamoto K, Shabe K, NhakT, Yanaga K, SugachK. Surgal treatment strategy for patnts wh stage hepatocellular carcoma. Surgery. 1996 May;119(5):517-22. do 10.1016/s0039-6060(96)80260-1. Donner A. Approaches to sample se estatn the desn of clal trls--a revw. Stat Med. 1984 Jul-Sep;3(3):199-214. do 10.1002/s.4780030302. Erratum : Stat Med 1990 Oct;9(10):1228. Asia-Pacific Multi-Centre Randomized Trial of Laparoscopic Versus Open Major Hepatectomy for Hepatocellular Carcinoma (AP-LAPO Trial)
Medientyp: report
Sonstiges:
  • Nachgewiesen in: ClinicalTrials.gov
  • Sprachen: English

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