Two Cu(ii)-based coordination polymers: Crystal structures and treatment activity on periodontitis
In: Open Chemistry, Jg. 19 (2021), Heft 1, S. 1287-1293
Online
academicJournal
Zugriff:
Two new Cu(ii)-based coordination polymers (CPs) with the chemical formulae of [CuL(bimmb)0.5]n (1, bimmb is 4-bis(imidazole-1-ylmethyl)benzene) and [CuL(bbibp)]n (2, bbibp is 4,4'-bis(benzoimidazo-1-yl)biphenyl) have been successfully prepared by the reaction of 3,3'-azodibenzoic acid (H2L) ligand and metal salt Cu(NO3)2·3H2O in the presence of different nitrogen-donor coligands. In the bioactive evaluation experiments, the treatment activity of the prepared CPs against periodontitis was examined. Enzyme-linked immunosorbent assay detection was used to test interleukin-18 (IL-18) and IL-6 contents released into the gingival crevicular fluid after the treatment of above CPs, and the real-time reverse transcription polymerase chain reaction was subsequently performed to measure the relative expression level of HmuY gene in the Porphyromonas gingivalis.
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Two Cu(ii)-based coordination polymers: Crystal structures and treatment activity on periodontitis
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Autor/in / Beteiligte Person: | Yipu, Xu ; Zhifang, Wu ; Xiangzhe, Zhao ; Xiangchun, Li |
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Zeitschrift: | Open Chemistry, Jg. 19 (2021), Heft 1, S. 1287-1293 |
Veröffentlichung: | De Gruyter, 2021 |
Medientyp: | academicJournal |
ISSN: | 2391-5420 (print) |
DOI: | 10.1515/chem-2021-0119 |
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