Improving Post-Discharge Medication Adherence in Patients with CVD: A Pilot Randomized Trial
In: Arquivos Brasileiros de Cardiologia, Jg. 103 (2014), Heft 6, S. 503-512
Online
academicJournal
Zugriff:
Background: Effective interventions to improve medication adherence are usually complex and expensive. Objective: To assess the impact of a low-cost intervention designed to improve medication adherence and clinical outcomes in post-discharge patients with CVD. Method: A pilot RCT was conducted at a teaching hospital. Intervention was based on the four-item Morisky Medication Adherence Scale (MMAS-4). The primary outcome measure was medication adherence assessed using the eight-item MMAS at baseline, at 1 month post hospital discharge and re-assessed 1 year after hospital discharge. Other outcomes included readmission and mortality rates. Results: 61 patients were randomized to intervention (n = 30) and control (n = 31) groups. The mean age of the patients was 61 years (SD 12.73), 52.5% were males, and 57.4% were married or living with a partner. Mean number of prescribed medications per patient was 4.5 (SD 3.3). Medication adherence was correlated to intervention (p = 0.04) and after 1 month, 48.4% of patients in the control group and 83.3% in the intervention group were considered adherent. However, this difference decreased after 1 year, when adherence was 34.8% and 60.9%, respectively. Readmission and mortality rates were related to low adherence in both groups. Conclusion: The intervention based on a validated patient self-report instrument for assessing adherence is a potentially effective method to improve adherent behavior and can be successfully used as a tool to guide adherence counseling in the clinical visit. However, a larger study is required to assess the real impact of intervention on these outcomes.
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Improving Post-Discharge Medication Adherence in Patients with CVD: A Pilot Randomized Trial
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Autor/in / Beteiligte Person: | Oliveira-Filho, Alfredo D. ; Morisky, Donald E. ; Costa, Francisco A. ; Pacheco, Sara T. ; Neves, Sabrina F. ; Lyra-Jr, Divaldo P. |
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Zeitschrift: | Arquivos Brasileiros de Cardiologia, Jg. 103 (2014), Heft 6, S. 503-512 |
Veröffentlichung: | Sociedade Brasileira de Cardiologia (SBC), 2014 |
Medientyp: | academicJournal |
ISSN: | 1678-4170 (print) |
DOI: | 10.5935/abc.20140151 |
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