DYNAMICS OF ELECTROPHORETIC ACTIVITY OF THE BUCCAL EPITHELIUM CELLS USING MODIFIED REMOVABLE DENTURE WITH HYDROGEL ON THE BASIS OF ADHESIVE ACTIVE POLYMER 'AKRILAN-LPI' WITH ANTISEPTIC AT CHRONIC GENERALIZED PERIODONTITIS

The treatment of patients with generalized periodontitis requires the involvement both therapeutic and surgical methods, during that it takes after shows the removal of teeth, including frontal group, which demands on aesthetic reasons their substitution on temporary, most often by removable dentures. At the same time providing of reliable and accelerated healing of the wound surface after remove of the teeth under the basis of temporary denture is important. During the study of home hydrogel was used on the basis of adhesive active polymer, worked out by the workers of the Lviv Polytechnic National University, which creates the possibility of prevention and treatment of local infectious inflammatory phenomena due to sorption of alcohol-soluble and water-soluble medications with the next local, prolonged desorption in the oral mucosal membrane in composition of removable denture. One of the effective methods of determination of effectiveness of proposed method is the definition of indicators of cell electrophoresis of the buccal epithelium, which represents reliable data of the homeostasis of organs and tissues. Thus, the aim of the study is an analysis of electrophoretic activity of the buccal epithelium cells with the use of modified removable denture with hydrogel on the basis of adhesive active polymer “Akrilan-LPI” with chlorhexidine bigluconate at chronic generalized periodontitis. The study included 86 patients with chronic generalized periodontitis, who needed removal of 2 and more teeth with the next orthopedic rehabilitation by removable dentures. The control and main groups were divided by the age into two subgroups: old age 55−74 and senile age 75−90 years. It was taken initial indicators and conducted sampling of material on 3, 14, 30 days after fixation of denture. It is set on the basis of analysis of the obtained data of electrophoretic activity of the buccal epithelium cells that the use of modified removable denture with hydrogel on the basis of adhesive active polymer “Akrilan-LPI” with chlorhexidine bigluconate in the composition of hydrogel at chronic generalized periodontitis in patients of elderly and senile age effectively supports and improves the functional reactions in the organism in general and the oral cavity in particular. The dependence of electrophoretic activity of the buccal epithelium cells in age gradation was revealed.