Risk score to stratify miscarriage risk levels in preconception women
In: Scientific Reports, Jg. 11 (2021), Heft 1, S. 1-11
Online
academicJournal
Zugriff:
Abstract Spontaneous miscarriage is one of the most common complications of pregnancy. Even though some risk factors are well documented, there is a paucity of risk scoring tools during preconception. In the S-PRESTO cohort study, Asian women attempting to conceive, aged 18-45 years, were recruited. Multivariable logistic regression model coefficients were used to determine risk estimates for age, ethnicity, history of pregnancy loss, body mass index, smoking status, alcohol intake and dietary supplement intake; from these we derived a risk score ranging from 0 to 17. Miscarriage before 16 weeks of gestation, determined clinically or via ultrasound. Among 465 included women, 59 had miscarriages and 406 had pregnancy ≥ 16 weeks of gestation. Higher rates of miscarriage were observed at higher risk scores (5.3% at score ≤ 3, 17.0% at score 4–6, 40.0% at score 7–8 and 46.2% at score ≥ 9). Women with scores ≤ 3 were defined as low-risk level (
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Risk score to stratify miscarriage risk levels in preconception women
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Autor/in / Beteiligte Person: | Xin Hui Choo ; Chee Wai Ku ; Yin Bun Cheung ; Godfrey, Keith M. ; Chong, Yap-Seng ; Lynette Pei-Chi Shek ; Kok Hian Tan ; Thiam Chye Tan ; Nadarajah, Sadhana ; Fabian Kok Peng Yap ; Colega, Marjorelee T. ; Mary Foong-Fong Chong ; Chan, Shiao-Yng ; See Ling Loy ; Jerry Kok Yen Chan |
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Zeitschrift: | Scientific Reports, Jg. 11 (2021), Heft 1, S. 1-11 |
Veröffentlichung: | Nature Portfolio, 2021 |
Medientyp: | academicJournal |
ISSN: | 2045-2322 (print) |
DOI: | 10.1038/s41598-021-91567-8 |
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