Zn(OAc)2•2H2O-catalyzed efficient synthesis of 5-Substituted 1H-tetrazoles
In: Current Chemistry Letters, Jg. 12 (2023), Heft 3, S. 509-518
Online
academicJournal
Zugriff:
In this communication, condensation from different aromatic, aliphatic and heteroaromatic aldehydes, hydroxyl amine, and sodium azide in toluene reflux was used to produce electronically and structurally distinct tetrazoles with a range of yields 5-94%. Zn(OAc)2•2H2O (10 mol%) was used as a catalyst in the synthesis, which was eco-friendly, readily available, and affordable. The IR, NMR, and mass spectral studies were utilized in order to carry out a comprehensive characterization for all the 5-aryl tetrazole derivatives. This approach contributes to the current chemical synthesis of 5-substituted-1H-tetrazoles in an appealing and convenient manner thanks to its quick reaction times, good to exceptional yields, safe process, and straightforward workup.
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Zn(OAc)2•2H2O-catalyzed efficient synthesis of 5-Substituted 1H-tetrazoles
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Autor/in / Beteiligte Person: | Kokane Balaji Digambar ; Varala, Ravi ; Patil, S. G. |
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Zeitschrift: | Current Chemistry Letters, Jg. 12 (2023), Heft 3, S. 509-518 |
Veröffentlichung: | Growing Science, 2023 |
Medientyp: | academicJournal |
ISSN: | 1927-7296 (print) ; 1927-730X (print) |
DOI: | 10.5267/j.ccl.2023.3.005 |
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