The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion
In: Nature Communications, Jg. 8 (2017), Heft 1, S. 1-15
Online
academicJournal
Zugriff:
The role of long noncoding RNAs in regulating T-cell differentiation within the tumour microenvironment is unclear. Here the authors identify a lncRNA that, through direct interactions with EGFR, promotes T-regulatory cell differentiation within the microenvironment of hepatocellular carcinoma, thus promoting tumour growth via immune suppression.
Titel: |
The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion
|
---|---|
Autor/in / Beteiligte Person: | Jiang, Runqiu ; Tang, Junwei ; Chen, Yun ; Deng, Lei ; Ji, Jie ; Xie, Yu ; Wang, Ke ; Jia, Wei ; Chu, Wen-Ming ; Sun, Beicheng |
Link: | |
Zeitschrift: | Nature Communications, Jg. 8 (2017), Heft 1, S. 1-15 |
Veröffentlichung: | Nature Portfolio, 2017 |
Medientyp: | academicJournal |
ISSN: | 2041-1723 (print) |
DOI: | 10.1038/ncomms15129 |
Schlagwort: |
|
Sonstiges: |
|