The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
In: Nature Communications, Jg. 13 (2022), Heft 1, S. 1-19
Online
academicJournal
Zugriff:
The functions of specific lipids in autophagosome biogenesis are not entirely clear. Here, the authors show that the ER protein GRAMD1C, a cholesterol transport protein, suppresses autophagy initiation and has roles in mitochondrial cholesterol homeostasis and respiration.
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The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
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Autor/in / Beteiligte Person: | Matthew Yoke Wui Ng ; Charsou, Chara ; Lapao, Ana ; Singh, Sakshi ; Trachsel-Moncho, Laura ; Schultz, Sebastian W. ; Nakken, Sigve ; Munson, Michael J. ; Simonsen, Anne |
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Zeitschrift: | Nature Communications, Jg. 13 (2022), Heft 1, S. 1-19 |
Veröffentlichung: | Nature Portfolio, 2022 |
Medientyp: | academicJournal |
ISSN: | 2041-1723 (print) |
DOI: | 10.1038/s41467-022-33933-2 |
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