EFEITO DO EXTRATO AQUOSO DE PRÓPOLIS MARROM SOBRE A PRODUÇÃO DE IFN-γ APÓS IMUNIZAÇÃO CONTRA PARVOVÍRUS CANINO (CPV) E CORONAVÍRUS CANINO (CCoV)
In: Ciência Animal Brasileira, Jg. 16 (2015), Heft 2, S. 235-242
Online
academicJournal
Zugriff:
The purpose of this study was to evaluate the imunnostimulatory adjuvant capacity of water extract from brown propolis (WEBP) when added to a vaccine against canine parvovirus (CPV) and canine coronavirus (CCoV), regarding the production of IFN-γ. Mice were vaccinated with CPV and CCoV (3.0 x 106 TCID50) with or without 400 µg/dose of WEBP. Thirty days after the third dose, splenocytes were cultured to measure the expression levels of IFN-γ mRNA in the immunized animals. Increased levels of IFN-γ mRNA expression for CCoV were evidenced by RT-PCR, in the splenocytes of mice inoculated with the vaccine containing 400 μg/dose of WEBP, demonstrating the ability of propolis to stimulate cellular immune responses against the antigens of this virus. In contrast, the levels of IFN-γ to CPV were not influenced by the presence of WEBP.
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EFEITO DO EXTRATO AQUOSO DE PRÓPOLIS MARROM SOBRE A PRODUÇÃO DE IFN-γ APÓS IMUNIZAÇÃO CONTRA PARVOVÍRUS CANINO (CPV) E CORONAVÍRUS CANINO (CCoV)
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Autor/in / Beteiligte Person: | Maureen Hoch Vieira Fernandes ; Lilian das Neves Ferreira ; Gilberto D'Avila Vargas ; Fischer, Geferson ; Silvia de Oliveira Hübner |
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Zeitschrift: | Ciência Animal Brasileira, Jg. 16 (2015), Heft 2, S. 235-242 |
Veröffentlichung: | Universidade Federal de Goiás, 2015 |
Medientyp: | academicJournal |
ISSN: | 1518-2797 (print) ; 1809-6891 (print) |
DOI: | 10.1590/1089-6891v16i223458 |
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