Inhibiting effect of D1, but not D2 antagonist administered to the striatum on retention of passive avoidance in the chick
In: Neurobiology of learning and memory (Print), Jg. 81 (2004), Heft 2, S. 155-158
academicJournal
- print; 4; 20 ref
Zugriff:
The avian lobus parolfactorius, equivalent to the medial striatum (caudate-putamen) of mammals, has been shown to be of crucial importance in passive avoidance training in day-old domestic chicks, where the aversive stimulus is the bitter tasting substance methylanthranilate. Here we report that the specific Dl antagonist SCH23390, injected into the lobus parolfactorius of day-old chicks (Gallus domesticus) prior to training, impaired performance on testing 30 min post-training at low doses (0.5 and 25 nmol). Sulpiride, a D2 antagonist, had no significant effect on performance in comparable doses. The early D1 activation may signify an essential mechanism leading to storage itself or to the canalisation of the relevant association to a permanent store.
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Inhibiting effect of D1, but not D2 antagonist administered to the striatum on retention of passive avoidance in the chick
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Autor/in / Beteiligte Person: | KABAI, Peter ; STEWART, Michael G ; TARCALI, Jozsef ; CSILLAG, Andras |
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Zeitschrift: | Neurobiology of learning and memory (Print), Jg. 81 (2004), Heft 2, S. 155-158 |
Veröffentlichung: | Amsterdam: Elsevier, 2004 |
Medientyp: | academicJournal |
Umfang: | print; 4; 20 ref |
ISSN: | 1074-7427 (print) |
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