Depressive symptoms are independently correlated with lipid peroxidation in a female population: Comparison with vitamins and carotenoids
In: Journal of psychosomatic research, Jg. 56 (2004), Heft 1, S. 53-58
academicJournal
- print; 6; 43 ref
Zugriff:
Objective: Lipid peroxidation (LPO) is involved in oxidative tissue injuries. The present investigation examined the association between LPO and psychological depressive symptoms. Methods: A cross-sectional study was conducted on 66 female volunteers aged 38-70. Lipid peroxides (LOOH) in serum were evaluated by hemoglobin-methylene blue (Hb-MB) method; additionally, serum antioxidants were also detected. To assess depressive symptoms, the Center for Epidemiologic Studies Depression (CES-D) Scale and a subscale in the 28-item General Health Questionnaire (GHQ) were applied. Results: LOOH concentration displayed a significant positive correlation with CES-D and GHQ depression scores. Multiple regression analysis was performed in which LOOH concentration served as a dependent variable and CES-D scores and antioxidants as independent variables. Consequently, CES-D scores demonstrated significant positive correlation with LOCH. Conclusions: The positive relationship between depressive symptoms and LPO in a female population may support the hypothesis that LPO may affect depressive symptoms.
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Depressive symptoms are independently correlated with lipid peroxidation in a female population: Comparison with vitamins and carotenoids
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Autor/in / Beteiligte Person: | TSUBOI, Hirohito ; SHIMOI, Kayoko ; KINAE, Naohide ; OGUNI, Itaro ; HORI, Reiko ; KOBAYASHI, Fumio |
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Zeitschrift: | Journal of psychosomatic research, Jg. 56 (2004), Heft 1, S. 53-58 |
Veröffentlichung: | Amsterdam; New York, NY: Elsevier, 2004 |
Medientyp: | academicJournal |
Umfang: | print; 6; 43 ref |
ISSN: | 0022-3999 (print) |
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