Rapid Antidepressant Effect of Ketamine Anesthesia During Electroconvulsive Therapy of Treatment-Resistant Depression: Comparing Ketamine and Propofol Anesthesia

OKAMOTO, Nagahisa ; NAKAI, Tetsuji ; et al.

In: ECT in the 21st Century: Optimizing Treatment. State of the Art, Jg. 26 (2010), Heft 3, S. 223-227

academicJournal - print; 5; 19 ref

Background: Reports of the superiority of the antidepressant effect of ketamine during the conduct of electroconvulsive therapy (ECT) have been limited. We conducted an open-label trial of ketamine to determine whether ketamine as the anesthetic during ECT would provide a greater antidepressant effect than the antidepressant effect obtained with propofol. Methods: Between April 2006 and April 2007, 31 inpatients with treatment-resistant depression gave written consent for ECT and to participate in this study. An anesthesiologist who was unaware of the mental symptoms of the subjects assigned them to receive propofol or ketamine anesthetic according to the preferences of the patients, and the patients underwent 8 ECT sessions for 4 weeks. The Hamilton Depression Rating Scale (HDRS) was valuated before ECT and after the completion of the second, fourth, sixth, and eighth ECT sessions. Results: The HDRS scores improved earlier in the ketamine group, with decreases in HDRS scores that were significantly greater in the ketamine group. Conclusions: The results suggested that it is possible to improve symptoms of depression earlier by using ketamine anesthesia.

Titel:	Rapid Antidepressant Effect of Ketamine Anesthesia During Electroconvulsive Therapy of Treatment-Resistant Depression: Comparing Ketamine and Propofol Anesthesia
Autor/in / Beteiligte Person:	OKAMOTO, Nagahisa ; NAKAI, Tetsuji ; SAKAMOTO, Kota ; NAGAFUSA, Yuko ; HIGUCHI, Teruhiko ; NISHIKAWA, Toru ; LOO, Colleen
Link:	View record from FRANCIS Archive
Zeitschrift:	ECT in the 21st Century: Optimizing Treatment. State of the Art, Jg. 26 (2010), Heft 3, S. 223-227
Veröffentlichung:	Hagerstown, MD: Lippincott Williams & Wilkins, 2010
Medientyp:	academicJournal
Umfang:	print; 5; 19 ref
ISSN:	1095-0680 (print)
Schlagwort:	Antagoniste Antagonist Antagonista Récepteur NMDA NMDA receptor Receptor NMDA Récepteur glutamate Glutamate receptor Receptor glutámato Traitement Treatment Tratamiento Trouble de l'humeur Mood disorder Trastorno humor Anesthésie Anesthesia Anestesia Anesthésique général General anesthetic Anestésico general Antidépresseur Antidepressant agent Antidepresor Efficacité traitement Treatment efficiency Eficacia tratamiento Electroconvulsivothérapie Electroconvulsive therapy Terapia electroconvulsiva Etat dépressif Depression Estado depresivo Etude comparative Comparative study Estudio comparativo Etude longitudinale Follow up study Estudio longitudinal Homme Human Hombre Kétamine Ketamine Ketamina Propofol Psychotrope Psychotropic Psicotropo Résistance traitement Treatment resistance Resistencia tratamiento Rôle thérapeutique Therapeutic role Función terapéutica Substance toxicomanogène Drug of abuse Sustancia toxicomanógena Phencyclidine dérivé antidepressant response electroconvulsive therapy (ECT) ketamine treatment-resistant depression Sciences biologiques et medicales Biological and medical sciences Sciences medicales Medical sciences Pharmacologie. Traitements medicamenteux Pharmacology. Drug treatments Neuropharmacologie Neuropharmacology Psychoanaleptiques: stimulant snc, antidépresseur, nootrope, normothymique..., (maladie d'alzheimer) Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychopathologie. Psychiatrie Psychopathology. Psychiatry Thérapeutiques Treatments Anesthesie. Reanimation. Transfusion. Therapie cellulaire et therapie genique Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthésie selon le type d'intervention Anesthesia depending on type of surgery Neurochirurgie Neurosurgery Psychologie. Psychanalyse. Psychiatrie Psychology. Psychoanalysis. Psychiatry PSYCHOPATHOLOGIE. PSYCHIATRIE Psychopharmacologie Psychopharmacology Psychoanaleptiques: stimulant SNC antidépresseur, nootrope, normothymique… Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer… Cognition Pharmacology drugs Pharmacologie, galénique Psychology, psychopathology, psychiatry Psychologie, psychopathologie, psychiatrie
Sonstiges:	Nachgewiesen in: FRANCIS Archive Sprachen: English Original Material: INIST-CNRS Document Type: Article File Description: text Language: English Author Affiliations: Department of Psychiatry, National Center Hospital of Neurology and Psychiatry, Kodaira City, Japan ; Department of Anesthesiology, National Center Hospital of Neurology and Psychiatry, Kodaira City, Japan ; Section of Psychiatry and Behavioral Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan ; School of Psychiatry, University of New South Wales, Sydney, Australia ; Black Dog Institute, Prince of Wales Hospital, Randwick, Australia ; St George Hospital, Kogarah, Australia Rights: Copyright 2015 INIST-CNRS ; CC BY 4.0 ; Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

Klicken Sie ein Format an und speichern Sie dann die Daten oder geben Sie eine Empfänger-Adresse ein und lassen Sie sich per Email zusenden.

BibTeX Citavi, JabRef, u.a.
(Literaturverwaltung)

PDF kein Volltext!
(Merkzettel, Notizen)

RIS Endnote, Citavi u.a.
(Literaturverwaltung)

MODS
(XML zur Weiterverarbeitung)

oder

Wählen Sie das für Sie passende Zitationsformat und kopieren Sie es dann in die Zwischenablage, lassen es sich per Mail zusenden oder speichern es als PDF-Datei.

Gewünschter Zitations-Stil:

oder

Bitte prüfen Sie, ob die Zitation formal korrekt ist, bevor Sie sie in einer Arbeit verwenden. Benutzen Sie gegebenenfalls den "Exportieren"-Dialog, wenn Sie ein Literaturverwaltungsprogramm verwenden und die Zitat-Angaben selbst formatieren wollen.