One-Pot, Direct Incorporation of [11 C]CO 2 into Carbamates
Wiley-Blackwell, 2009
Online
academicJournal
Zugriff:
Why beat about the bush? An operationally simple and mild reaction based on the direct fixation of 11CO2 with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) has been developed for the synthesis of 11C-labeled carbamates at 75 °C within 10 minutes in radiochemical yields above 70 % (see scheme). This strategy should be immediately useful for the construction of new radiotracers for positron emission tomography and other applications.
Chemistry and Chemical Biology
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One-Pot, Direct Incorporation of [11 C]CO 2 into Carbamates
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Autor/in / Beteiligte Person: | Hooker, Jacob M ; Reibel, Achim T. ; Hill, Sidney M. ; Schueller, Michael J. ; Fowler, Joanna S. |
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Veröffentlichung: | Wiley-Blackwell, 2009 |
Medientyp: | academicJournal |
ISSN: | 1433-7851 (print) |
DOI: | 10.1002/anie.200900112 |
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