Analisis Penggunaan Antibiotika pada Pasien Penyakit Dalam di RSUD Dr. H. Slamet Martodirdjo Pamekasan dengan Metode ATC/DDD

Antimicrobial resistance is a global health problem, it can’t be eliminated but can be slowed down. The wise use of antibiotics is one way to overcome antimicrobial resistance. The Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/ DDD) method is used to assess the quantity of antibiotic use. The purpose of this study was to determine the value of DDD and DU 90% of antibiotics. This research is a descriptive-analytic (cross-sectional) study with retrospective data collection in patients with diseases in RSUD Dr. H. Slamet Martodirdjo Pamekasan during the January-March 2019 period. The inclusion criteria were inpatients with internal medicine using antibiotics. Exclusion criteria were patients using topical antibiotic preparations, patients who died during the study, and pediatric patients (<18 years). The number of samples obtained 482 patients who were further analyzed using the ATC/DDD method. The results showed the total DDD value of antibiotic use was 76.03/100 patient-days with the full length of stay (LOS) of patients being 2270 days. The antibiotic with the highest DDD value was ceftriaxone, 37.56/100 patient-days. While antibiotics that enter the DU 90% segment are ceftriaxone, ciprofloxacin, and levofloxacin, so their use should be monitored because of the potential risk of bacterial resistance to antibiotics