Efficient DBU accelerated synthesis of F-18-labelled trifluoroacetamides
2016
Online
Elektronische Ressource
Nucleophilic F-18-fluorination of bromodifluoromethyl derivatives was performed using [F-18] Bu4NF in the presence of DBU(1,8-diazabicyclo[5.4.0]undec-7-ene). This novel procedure provided a diverse set of [F-18] trifluoroacetamides in good to excellent radiochemical conversions. A mechanism where DBU acts as organomediator in this transformation is proposed.
Titel: |
Efficient DBU accelerated synthesis of F-18-labelled trifluoroacetamides
|
---|---|
Link: | |
Veröffentlichung: | 2016 |
Medientyp: | Elektronische Ressource |
DOI: | 10.1039.c6cc08535k |
Schlagwort: |
|
Sonstiges: |
|