MQF and buffered MQF: quotient filters for efficient storage of k-mers with their counts and metadata.
In: BMC bioinformatics; vol 22, iss 1, 71; 1471-2105; (2021)
Online
Elektronische Ressource
BackgroundSpecialized data structures are required for online algorithms to efficiently handle large sequencing datasets. The counting quotient filter (CQF), a compact hashtable, can efficiently store k-mers with a skewed distribution.ResultHere, we present the mixed-counters quotient filter (MQF) as a new variant of the CQF with novel counting and labeling systems. The new counting system adapts to a wider range of data distributions for increased space efficiency and is faster than the CQF for insertions and queries in most of the tested scenarios. A buffered version of the MQF can offload storage to disk, trading speed of insertions and queries for a significant memory reduction. The labeling system provides a flexible framework for assigning labels to member items while maintaining good data locality and a concise memory representation. These labels serve as a minimal perfect hash function but are ~ tenfold faster than BBhash, with no need to re-analyze the original data for further insertions or deletions.ConclusionsThe MQF is a flexible and efficient data structure that extends our ability to work with high throughput sequencing data.
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MQF and buffered MQF: quotient filters for efficient storage of k-mers with their counts and metadata.
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Autor/in / Beteiligte Person: | Shokrof, Moustafa |
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Quelle: | BMC bioinformatics; vol 22, iss 1, 71; 1471-2105; (2021) |
Veröffentlichung: | 2021 |
Medientyp: | Elektronische Ressource |
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