Results of Simultaneous Pancreas and Kidney Transplantation after Nearly 10 Years of Experience in our Hospital
Morressier, 2017
Online
unknown
Introduction: Simultaneous Pancreas and Kidney (SPK) transplantation is the most suitable option for patients with Diabetes Mellitus (DM) and Chronic Renal Failure (CRF) and improves quality of life of these patients.Objective and Methods: evaluate the results of our SPK transplantation in our hospital. From 27/02/2009 to 20/11/2018 70 patients received a pancreas transplantation, 68 SPK and 2 patients received a second pancreas after kidney (PAK) because of a failure of the pancreas graft surgery, (these two were excluded from the study). Retrospective study where we analyzed demographic characteristics, evolution and survival of the grafts and patients. Kidney graft failure was need of restarting dialysis, and pancreas failure, need of insulin administration. Student t, X2 and Mann Whitney tests were done.Results: in this period 68 SPK were carried out in the University Hospital of Salamanca, Spain. Recipients average age was 40.6 +/- 7.75. 50 men (73.52%) and 18 women (26.47%). 7 patients received a pre-emptive SPK (10.29%). 19 (27.94%) were in Peritoneal dialysis (PD) and 42 (61,76%) were receiving Hemodialysis (HD). Pancreas cold ischemia time (CIT) average 11 hours 20 minutes and renal CIT average14 hours 10 minutes. 3 patients died so patient survival was 95.58%. 7 kidneys were lost but 4 of those patients had already received a second kidney transplantation. Renal survival was 85%, dead censored was 93%. Pancreas survival was 92% but dead censored was 97 %. Renal function and glycosylate hemoglobin are shown in the table 1. Of the values studied we didnu2019t find any association between them and either renal of pancreas graft failure. ConclusionsAfter nearly 10 years we can say that the SPK transplantation is the most suitable treatment for patients with DM and CRF. We didnu2019t find any statistical association between the reviewed values and the prognosis of this transplantation.Creatinine 1 year post-transplantation (post-tr)t1,15u00b10,31 mg/dlHbA1C 1 year post-trt5,33u00b10,48 %Creatinine 5 years post-trt1,22u00b10,29 mg/dl HbA1C 5 years post-trt5,41u00b1037 %Creatinine November 2018t1,19u00b1 0,28 mg/dlHbA1C November 2018t5,32u00b1 0,37 %
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Results of Simultaneous Pancreas and Kidney Transplantation after Nearly 10 Years of Experience in our Hospital
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Veröffentlichung: | Morressier, 2017 |
Medientyp: | unknown |
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