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- Nachgewiesen in: USPTO Patent Grants
- Sprachen: English
- Patent Number: 8,008,330
- Publication Date: August 30, 2011
- Appl. No: 12/549947
- Application Filed: August 28, 2009
- Assignees: Novartis AG (Basel, CH)
- Claim: 1. A combination which comprises (a) a platinum compound selected from the group consisting of oxaliplatin and carboplatin and (b) an epothilone derivative of formula I [chemical expression included] wherein A represents O, R is hydrogen or lower alkyl, and Z is O or a bond, in which the active ingredients (a) and (b) are present in each case in free form or in the form of a pharmaceutically acceptable salt and optionally at least one pharmaceutically acceptable carrier; for simultaneous, separate or sequential use.
- Claim: 2. Combination according to claim 1 , which is a combined preparation or a pharmaceutical composition.
- Claim: 3. Method of treating a warm-blooded animal having a proliferative disease selected from the group consisting of ovarian cancer, lung cancer, head or neck cancer, cervix cancer, prostate cancer or colon cancer comprising administering to the animal a combination according to claim 1 in a quantity which is jointly therapeutically effective against the proliferative disease and in which the compounds can also be present in the form of their pharmaceutically acceptable salts.
- Current U.S. Class: 514/365
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- Primary Examiner: Henley, III, Raymond J
- Attorney, Agent or Firm: Dohmann, George R.
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