Pre-corneal tear film thickness in humans measured with a novel technique
In: Molecular Vision, Jg. 17 (2011-03-22)
Online
academicJournal
- 756 - 767
PurposeThe purpose of this work was to gather preliminary data in normals and dry eye subjects, using a new, non-invasive imaging platform to measure the thickness of pre-corneal tear film.MethodsHuman subjects were screened for dry eye and classified as dry or normal. Tear film thickness over the inferior paracentral cornea was measured using laser illumination and a complementary metal–oxide–semiconductor (CMOS) camera. A previously developed mathematical model was used to calculate the thickness of the tear film by applying the principle of spatial auto-correlation function (ACF).ResultsMean tear film thickness values (±SD) were 3.05 μm (0.20) and 2.48 μm (0.32) on the initial visit for normals (n=18) and dry eye subjects (n=22), respectively, and were significantly different (p
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Pre-corneal tear film thickness in humans measured with a novel technique
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Autor/in / Beteiligte Person: | Azartash, Kaveh ; Kwan, Justin ; Paugh, Jerry R. ; Nguyen, Andrew Loc ; Jester, James V. ; Gratton, Enrico |
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Zeitschrift: | Molecular Vision, Jg. 17 (2011-03-22) |
Veröffentlichung: | eScholarship, University of California, 2011 |
Medientyp: | academicJournal |
Umfang: | 756 - 767 |
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