The role of CuI in the siloxane-mediated Pd-catalyzed cross-coupling reactions of aryl iodides with aryl lithium reagents
In: Chinese Chemical Letters, Jg. 32 (2021), Heft 1
Online
academicJournal
- 441 - 444
Experiments indicate that a catalytic amount of CuI plays an important role in the siloxane-mediated Pd-catalyzed cross-coupling reactions with the direct use of organolithium reagents. Addition of organolithium to the siloxane transfer agent generates an organosilicon intermediate. DFT calculations indicate that CuI initially accelerates the Si-Pd(II) transmetalation of the organosilicon intermediate by the formation of CuI2 -. Subsequently, CuI2 - works as a shuttle between the Si-Cu(I) and Cu(I)-Pd(II) transmetalation processes.
Titel: |
The role of CuI in the siloxane-mediated Pd-catalyzed cross-coupling reactions of aryl iodides with aryl lithium reagents
|
---|---|
Autor/in / Beteiligte Person: | Chen, Yu ; Zhang, Xiao ; Liu, Fang ; He, Gucheng ; Zhang, Ju ; Houk, KN ; Smith, Amos B ; Liang, Yong |
Link: | |
Zeitschrift: | Chinese Chemical Letters, Jg. 32 (2021), Heft 1 |
Veröffentlichung: | eScholarship, University of California, 2021 |
Medientyp: | academicJournal |
Umfang: | 441 - 444 |
Schlagwort: |
|
Sonstiges: |
|