Prenatal and postnatal small-quantity lipid-based nutrient supplements and childrens social-emotional difficulties at ages 9-11 y in Ghana: follow-up of a randomized controlled trial.
In: American Journal of Clinical Nutrition, Jg. 118 (2023-08-01), Heft 2
Online
academicJournal
BACKGROUND: Provision of small-quantity lipid-based nutrient supplements (SQ-LNSs) during early life improves growth and development. In the International Lipid-Based Nutrient Supplements DYAD-Ghana trial, prenatal and postnatal SQ-LNS reduced social-emotional difficulties at age 5 y, with greater effects among children in less-enriched home environments. OBJECTIVES: We aimed to investigate the effect of prenatal and postnatal SQ-LNS on childrens social-emotional problems at age 9-11 y. METHODS: In 2009-2011, 1320 pregnant women ≤20 wk gestation were randomly assigned to receive the following daily until 6 mo postpartum: 1) iron and folic acid until delivery, then placebo, 2) multiple micronutrients (MMNs), or 3) SQ-LNS (20 g/d). Children in group 3 received SQ-LNS from 6 to 18 mo. In 2021, we evaluated childrens social-emotional outcomes with 6 assessment tools that used caregiver, teacher, and/or self-report to measure socioemotional difficulties, conduct problems, temperament, mood, anxiety, and emotion management. RESULTS: We assessed outcomes in 966 children, comprising 79.4% of 1217 participants eligible for re-enrolment. No significant differences were found between the SQ-LNS and control (non-LNS groups combined) groups. Few children (
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Prenatal and postnatal small-quantity lipid-based nutrient supplements and childrens social-emotional difficulties at ages 9-11 y in Ghana: follow-up of a randomized controlled trial.
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Autor/in / Beteiligte Person: | Adu-Afarwuah, Seth ; Adjetey, Ebenezer ; Amponsah, Benjamin ; Bentil, Helena ; Guyer, Amanda ; Manu, Adom ; Mensah, Mavis ; Oaks, Brietta ; Ocansey, Maku ; Tan, Xiuping ; Dewey, Kathryn ; Hastings, Paul ; Prado, Elizabeth ; Arnold, Charles |
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Zeitschrift: | American Journal of Clinical Nutrition, Jg. 118 (2023-08-01), Heft 2 |
Veröffentlichung: | eScholarship, University of California, 2023 |
Medientyp: | academicJournal |
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