Rest‐Activity Rhythms and Cognitive Decline in Older Men: The Osteoporotic Fractures in Men Sleep Study
In: Journal of the American Geriatrics Society, Jg. 66 (2018-11-01), Heft 11
Online
academicJournal
- 2136 - 2143
OBJECTIVE:To examine rest-activity circadian rhythm (RAR) and cognitive decline in older men. DESIGN:Longitudinal. SETTING:Osteoporotic Fractures in Men (MrOS) and ancillary Outcomes of Sleep Disorders in Men (MrOS Sleep) studies. PARTICIPANTS:MrOS and MrOS Sleep participants (N=2,754; mean age 76.0 ± 5.3). MEASUREMENTS:The Modified Mini-Mental State examination (3MS) was used to assess cognition at baseline (2003-05) and follow-up examinations (2005-06 and 2007-09). Wrist actigraphy was used to measure 24-hour activity counts at baseline. RAR variables included amplitude (strength of activity rhythm), mesor (mean activity level), pseudo F-statistic (overall circadian rhythm robustness), and acrophase (time of daily peak activity). RESULTS:After an average of 3.4 ± 0.5 years, men with lower amplitudes, mesors, and pseudo F-statistics had greater decline in 3MS performance (amplitude: -0.7 points Q1 vs -0.5 points Q4, p
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Rest‐Activity Rhythms and Cognitive Decline in Older Men: The Osteoporotic Fractures in Men Sleep Study
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Autor/in / Beteiligte Person: | Rogers‐Soeder, Tara S ; Blackwell, Terri ; Yaffe, Kristine ; Ancoli‐Israel, Sonia ; Redline, Susan ; Cauley, Jane A ; Ensrud, Kristine E ; Paudel, Misti ; Barrett‐Connor, Elizabeth ; LeBlanc, Erin ; Stone, Katie ; Lane, Nancy E ; Tranah, Greg ; Group, for the Osteoporotic Fractures in Men Study Research |
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Zeitschrift: | Journal of the American Geriatrics Society, Jg. 66 (2018-11-01), Heft 11 |
Veröffentlichung: | eScholarship, University of California, 2018 |
Medientyp: | academicJournal |
Umfang: | 2136 - 2143 |
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