Partners in Crime: The Role of CMV in Immune Dysregulation and Clinical Outcome During HIV Infection
In: Current HIV/AIDS Reports, Jg. 13 (2016-02-01), Heft 1
Online
academicJournal
- 10 - 19
In the current era of combination antiretroviral therapy (ART), human immunodeficiency virus (HIV)-infected individuals are living longer and healthier lives. Nevertheless, HIV-infected persons are at greater risk for age-related disorders, which have been linked to residual immune dysfunction and inflammation. HIV-infected individuals are almost universally co-infected with cytomegalovirus (CMV) and both viruses are associated with inflammation-related morbidities. Therefore, a detailed investigation of the relationship between CMV and aging-related morbidities emerging during chronic HIV infection is warranted. Here, we review the literature on how CMV co-infection affects HIV infection and host immunity and we discuss the gaps in our knowledge that need elucidation.
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Partners in Crime: The Role of CMV in Immune Dysregulation and Clinical Outcome During HIV Infection
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Autor/in / Beteiligte Person: | Freeman, Michael L ; Lederman, Michael M ; Gianella, Sara |
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Zeitschrift: | Current HIV/AIDS Reports, Jg. 13 (2016-02-01), Heft 1 |
Veröffentlichung: | eScholarship, University of California, 2016 |
Medientyp: | academicJournal |
Umfang: | 10 - 19 |
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