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Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.
In: Contact Dermatitis, Jg. 71 (2014), Heft 1, S. 31-34
Online
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Zugriff:
Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.
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Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.
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Autor/in / Beteiligte Person: | Bruze, Magnus ; Isaksson, Marléne ; Gruvberger, Birgitta ; Andersen, Klaus E ; Gonçalo, Margarida ; Goossens, An ; Johansen, Jeanne D ; Maibach, Howard I ; Rustemeyer, Thomas ; Le Coz, Christophe-J ; White, Ian R |
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Zeitschrift: | Contact Dermatitis, Jg. 71 (2014), Heft 1, S. 31-34 |
Veröffentlichung: | 2014 |
Medientyp: | unknown |
ISSN: | 0105-1873 (print) |
DOI: | 10.1111/cod.12241 |
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