Towards industrial pentose-fermenting yeast strains
In: Applied Microbiology and Biotechnology, Jg. 74 (2007), Heft 5, S. 937-953
Online
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Zugriff:
Production of bioethanol from forest and agricultural products requires a fermenting organism that converts all types of sugars in the raw material to ethanol in high yield and with a high rate. This review summarizes recent research aiming at developing industrial strains of Saccharomyces cerevisiae with the ability to ferment all lignocellulose-derived sugars. The properties required from the industrial yeast strains are discussed in relation to four benchmarks: (1) process water economy, (2) inhibitor tolerance, (3) ethanol yield, and (4) specific ethanol productivity. Of particular importance is the tolerance of the fermenting organism to fermentation inhibitors formed during fractionation/pretreatment and hydrolysis of the raw material, which necessitates the use of robust industrial strain background. While numerous metabolic engineering strategies have been developed in laboratory yeast strains, only a few approaches have been realized in industrial strains. The fermentation performance of the existing industrial pentose-fermenting S. cerevisiae strains in lignocellulose hydrolysate is reviewed. Ethanol yields of more than 0.4 g ethanol/g sugar have been achieved with several xylose-fermenting industrial strains such as TMB 3400, TMB 3006, and 424A(LNF-ST), carrying the heterologous xylose utilization pathway consisting of xylose reductase and xylitol dehydrogenase, which demonstrates the potential of pentose fermentation in improving lignocellulosic ethanol production.
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Towards industrial pentose-fermenting yeast strains
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Autor/in / Beteiligte Person: | Hahn-Hägerdal, Bärbel ; Karhumaa, Kaisa ; Fonseca, Cesar ; Spencer-Martins, Isabel ; Gorwa-Grauslund, Marie-Francoise |
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Zeitschrift: | Applied Microbiology and Biotechnology, Jg. 74 (2007), Heft 5, S. 937-953 |
Veröffentlichung: | 2007 |
Medientyp: | unknown |
ISSN: | 1432-0614 (print) |
DOI: | 10.1007/s00253-006-0827-2 |
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